ABSTRACT
Objectives: To compare the effects of two different intravenous lipid emulsions on solubleadhesion markers in preterm infants with sepsis. Methods: This randomized controlled pilottrial was conducted from February 2016 to February 2017. 40 preterm infants with sepsiswere enrolled and assigned to receive either Medium chain triglyceride-Olive-Fish-Soy lipidemulsion (MOFS-LE) or soybean oil-based lipid emulsion (S-LE). Outcomes of the studywere changes in sICAM-1 and leukocyte integrin β2 levels, and growth after 7 days ofintervention. Results: Leukocyte integrin β2 was significantly higher in MOFS-LE group. Nostatistically significant differences were observed for sICAM-1, duration of mechanicalventilation and antibiotics treatment, and mortality rate. Conclusions: Leukocyte integrin β2was significantly higher in preterm septic neonates who received MOFS-LE